The tag has no usage guidance.

learn more… | top users | synonyms

0
votes
1answer
106 views

How different is the working of SNN (Spiking Neural Network) as compared to a real Neuron System in biological systems?

Assuming its one step closer to realism as compared to ANN, DNNs and other Neural Network models, what are the primary differences between a real neuron system and SNN?
0
votes
0answers
45 views

Graph theoretical approach to compare n pair of variables along a set of interval

I am dealing a bioinformatics problem and need help in approaching it in the right direction. I have a set of variables that represent different kinds of genomic data and are real valued. I am trying ...
1
vote
1answer
46 views

How is n-gram different from k-mer?

How is n-gram different from k-mer? Both seem to be (n or k) length substrings of a larger string. Are these just terms common with different practitioners? viz. Computer Scientists and ...
2
votes
1answer
63 views

Why doesn't the Needleman-Wunsch algorithm find solutions that begin with a gap?

I have implemented in C++ the Needleman-Wunsch algorithm for pairwise sequence alignment using the following scores: +1 for match (regardless of base), -1 gap penalty and -1 for a mismatch. Given two ...
0
votes
0answers
20 views

Are there any algorithms or researches on finding local alignments in partially ordered sequences?

The question is a bit unclear, so let me explain. Finding local alignments in sequences like protein sequence is a well studied area in bioinformatics, and I do not think there is any lack of ...
1
vote
0answers
32 views

Multiple sequence Progressive alignment example using five sequences

I tried to find sources that explain multiple sequence alignment with an example using progressive alignment, but I couldn't find one. I actually know till creating a guide tree, after creating a ...
2
votes
1answer
178 views

Programming languages for genetic engineering [closed]

I'm interested in getting a Ph.D. and would love to work on a project such the GEC project at Microsoft Research, which studies the application of programming languages for synthetic biology and ...
-1
votes
1answer
69 views

Selecting a M.S. in CS focus [closed]

I need to pick a focus in my Masters program. The running candidates are Networking Bioinformatics Data mining Computer Image Recognition In order to avoid this becoming a discussion, I'd be ...
5
votes
1answer
86 views

Borrowing bioinformatic methods in other fields

Have the bioinformatic methods like sequence analysis, genome annotation, comparative genomics (and many others), been applied to solve problems outside the field of bioinformatics?
3
votes
1answer
241 views

A framework to capture common variation of sequence alignments

The global alignment problem can be generalized by setting the cost of some boundary gaps to 0. Gaps at both end in both strings have 0 cost, then we get the semiglobal alignment. Gaps are at the ...
8
votes
1answer
193 views

Seeking popular science book on bioinformatics or computational genomics

An intelligent 15-year-old I know is interested in both computer science and genetics. I told her that these fields make an excellent combination. I'd like to give her a book on bioinformatics or ...
2
votes
1answer
161 views

Mutual information and moment generating functions

I went to listen to a workshop and someone from the audience asked the presenter how the moments can improve the mutual information. I am learning about MI (Mutual Information) so didn't have enough ...
11
votes
4answers
274 views

Introductory books on nature sciences behind bioinformatics

My question goes to those who are concerned with computational biology algorithmics. I'm going to take a course on bioinformatics this fall; the problem, however, is that I have too little background ...