Definitions
I'm using the definition of big-omega from Wikipedia and making it more explicit:
$$\left[ f(n) \in \Omega(g(n)) \right] \:\Longleftrightarrow\:
\left[ \exists k \in \mathbb{R}^+, \exists n_0 \in \mathbb{N}, \forall n \in \mathbb{N}, \left[(n > n_0) \Rightarrow (f(n) \ge k \cdot g(n)) \right] \right]$$
In your statement you have $f(n) = n^5 - 3n^4 + \log(n^{10})$, and $g(n) = n^5$.
Intuitions
As $n$ gets larger, $f(n)$ essentially behaves like $n^5$ (which matches $g(n)$). This is because both the $-3n^4$ and $\log(n^{10})$ terms grow more slowly (see big-O theory). So the value of $k$ to satisfy the big-omega definition should be somewhere around $1$.
We (probably) can't choose $k = 1$ because $n^5 - 3n^4 < n^5$ for all $n > 0$, which means $f(n) < k \cdot g(n)$. We can disregard the $\log(n^{10})$ term because it grows slower than $-3n^4$. So we'll choose some $0 < k < 1$.
Solution
Let's choose $k = \frac{1}{2}$. (Actually any $k$ slightly less than $1$ will also work.)
Solve for the break-even point of $n^5 - 3n^4 = k \cdot n^5$, and we get $n = 6$. Choose $n_0 = 6$.
Now to confirm: Is it true that for all $n > 6$, we have $n^5 - 3n^4 \ge \frac{1}{2} n^5$? Yes, because:
$n > 6$ (left side of implication)
$\Rightarrow\: n \cdot n^4 > 6 \cdot n^4$ (multiply by $n^4$)
$\Rightarrow\: n^5 > 6n^4$ (simplify)
$\Rightarrow\: \frac{1}{2} n^5 > \frac{1}{2} 6n^4$ (multiply by $\frac{1}{2}$)
$\Rightarrow\: \frac{1}{2} n^5 > 3n^4$ (simplify)
$\Rightarrow\: \frac{1}{2} n^5 - 3n^4 > 3n^4 - 3n^4$ (subtract $3n^4$)
$\Rightarrow\: \frac{1}{2} n^5 - 3n^4 > 0$ (simplify)
$\Rightarrow\: \frac{1}{2} n^5 - 3n^4 + \frac{1}{2} n^5 > \frac{1}{2} n^5$ (subtract $\frac{1}{2} n^5$)
$\Rightarrow\: n^5 - 3n^4 > \frac{1}{2} n^5$ (simplify)
$\Rightarrow\: n^5 - 3n^4 \ge \frac{1}{2} n^5$. (weaken inequality)
Finally, because for all $n > 0$, we have $\log(n^{10}) > 0$, therefore $n^5 - 3n^4 + \log(n^{10}) > n^5 - 3n^4 \ge \frac{1}{2} n^5$.
Let $k = \frac{1}{2} \in \mathbb{R}^+$.
Let $n_0 = 6 \in \mathbb{N}$.
Let $n \in \mathbb{N}$ be arbitrary.
Assume $n > n_0$.
$\therefore n > 6$.
$\therefore \log(n^{10}) > 0$.
$\therefore \frac{1}{2} n^5 > 3n^4$.
$\therefore n^5 - 3n^4 > \frac{1}{2} n^5$.
$\therefore n^5 - 3n^4 + \log(n^{10}) \ge \frac{1}{2} n^5$.
$\therefore f(n) \ge k \cdot g(n)$.
$\therefore (n > n_0) \Rightarrow (f(n) \ge k \cdot g(n))$.
$\therefore \forall n \in \mathbb{N}, \left[ (n > n_0) \Rightarrow (f(n) \ge k \cdot g(n)) \right]$.
$\therefore \exists n_0 \in \mathbb{N}, \forall n \in \mathbb{N}, \left[ (n > n_0) \Rightarrow (f(n) \ge k \cdot g(n)) \right]$.
$\therefore \exists k \in \mathbb{R}^+, \exists n_0 \in \mathbb{N}, \forall n \in \mathbb{N}, \left[ (n > n_0) \Rightarrow (f(n) \ge k \cdot g(n)) \right]$.
$\therefore f(n) \in \Omega(g(n))$.