Complexity zoo https://complexityzoo.uwaterloo.ca/Complexity_Zoo:D#dtime states $DTIME(f(n))$ with $PP$ oracle is not in $P/Poly$ if $f(n)$ is superpolynomial.

We know $SUBEXP=\cap_{\epsilon>0}DTIME(2^{n^\epsilon})\not\subseteq DTIME(p(n))$ for any polynomial $p(n)$.

So do we have $SUBEXP^{PP}\not\subseteq P/Poly$? So can we say either $SUBEXP\not\subseteq P/Poly$ or ${PP}\not\subseteq P/Poly$ holds?

I am trying to understand if $C^O\not\subseteq D$ for classes $C,O,D$ then does it follow either $C\not\subseteq D$ or $O\not\subseteq D$?

In other words if we have two classes $C,O$ with $C\subseteq D$ and $O\subseteq D$ then does it mean $C^O\subseteq D$?