If you want to use L'Hopital's rule to prove $n^{a}=o(2^n)$ that is fairly easy.

Lets consider the lemma in [this question's accepted answer][1]. The problem reduces to calculate the limit:

$$ \lim_{n\to\infty} \frac{n^a}{2^n} $$

This limit is of the type "infinite divided by infinite". So we can try to use L'Hopital's rule. 

Let $f^i(n)$ be the ith derivative of $f(n)$ and $g^i(n)$ be the ith derivative of $g(n)$. Consider the following properties of $f(n)=n^a$ and $g(n)=2^n$:

$$f^i(n) = a(a-1)(a-2)...(a-i+2)(a-i+1)n^{a-i} $$
$$g^i(n) = 2^n*log^i(2)$$

As you can see the following LHopital's Rule's conditions comply:

- $f$ and $g$ are differentiable in the interval $]1,\infty[$.
- $g$ and $g'$ are nonzero in the interval $]1, \infty[$.
- As $n \rightarrow \infty$:

$$\frac{f(n)}{g(n)}\rightarrow \frac{\infty}{\infty}$$

This conditions also comply for the derivatives of $f$ and $g$.

Now we use L'Hopital's rule "a" times: We have to derive $f(n)$ and $g(n)$ "a" times and the result is:

$$ \lim_{n\to\infty} \frac{n^a}{2^n} =  \lim_{n\to\infty} \frac{a(a-1)(a-2)...(2)(1)*n^0}{2^n*log^a(2)} \rightarrow \frac{a(a-1)(a-2)...(2)(1)*1}{2^\infty*log^a(2)}= 0 $$

Finally the last condition of L'Hopital rule complies:

- The limit exist(in this case is defined).

and the limit is zero as requested so $n^{a}=o(2^n)$.

  [1]: https://cs.stackexchange.com/questions/824/sorting-functions-by-asymptotic-growth